Penetrex Review – Do Penetrex Capsules and Cream Work for Joint Pain?

Penetrex Review

Penetrex simplified

Penetrex is a joint supplement line that includes gels, creams, and capsules for joint pain relief. Some of the most popular versions of the product include Joint & Muscle Therapy Cream and Joint, Muscle & Nerve Support capsules.

However, both versions have limitations. The cream’s proprietary blend and absence of key ingredients raise concerns about its effectiveness for long-term joint health.

The capsules are a slightly better choice if you ask us since they don’t use proprietary blends. However, they lack the essential ingredients needed for comprehensive joint support and joint lubrication, such as selenium, bromelain, glucosamine, and MSM.

All in all, if you decide to go for capsules, you should get some pain relief in the long run if you use the product consistently, but don’t expect substantial results.

There are far better alternatives available on the market, far more effective than Penetrex, that use richer formulas. While these alternatives are way more expensive, they ensure you get what you’re paying for. Usually, the least expensive joint supplements are the least effective ones.

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>The Best Joint Supplements of The Year<

Penetrex – how does it work?

Penetrex is a line of joint supplements that aims to provide relief from joint and muscle discomfort. It offers two main versions: Penetrex Joint & Muscle Therapy Cream and Penetrex Joint, Muscle & Nerve Support capsules, each with a slightly different ingredient formula.

Both products are marketed as a tool to help eliminate joint and muscle pain, inflammation, and stiffness. To determine whether Penetrex works or not, we have to take a look at the ingredient formula in both the cream version and the capsules.

Core ingredients in Penetrex – What does Penetrex Have in It?

Penetrex Cream Ingredients

As seen on the label, Penetrex Joint & Muscle Therapy Cream includes a proprietary blend of ingredients, making it difficult to assess the exact doses and effectiveness of each ingredient. Another issue is that it lacks essential ingredients like MSM, selenium, bromelain, glucosamine, and turmeric, which are known for their positive impact on joint health.

This formula’s limitations and lack of transparency make it less than ideal for individuals seeking optimal support. You can’t be sure how effective and safe each ingredient is going to be if you don’t know the precise dosage of each individual ingredient.

Penetrex Capsules Ingredients

In comparison, Penetrex Joint, Muscle & Nerve Support capsules do not use a proprietary blend, which makes them a better choice than the cream. These capsules include Boswellia serrata, vitamin C, and other vitamins and minerals such as magnesium, zinc, and vitamin D.

While Boswellia serrata and vitamin C have shown some potential benefits for joint health, the absence of core ingredients makes us question Penetrex’s ability to address the complex needs of joint health. For example, selenium, bromelain, MSM, and glucosamine could have been added to enhance joint lubrication and promote connective tissue healing. They would also support cartilage health.

Overall, the line of Penetrex supplements does not contain comprehensive ingredient formulas for joint issues, and that’s why we can’t recommend them.

Looking for a different supplement?

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Instructions – How to Take Penetrex?

For Penetrex Joint & Muscle Therapy Cream, the recommended usage is to apply the cream to the affected area up to three times per day.

As for Penetrex Joint, Muscle & Nerve Support capsules, it is suggested to take two capsules daily for complete nerve, muscle, and joint support. Each bottle provides a 30-day supply.


A 2 Oz. pain relief cream from Penetrex is available for the price of $18.95 on the official site. The joint, muscle, and nerve support capsules are a bit more expensive, at $19.99 for a one-month supply.

Side effects

Penetrex capsules should be safe for most people and therefore shouldn’t cause any side effects. When it comes to the cream, it is not as safe due to a proprietary blend.

Who should not use Penetrex?

Pregnant or nursing women, children, people with allergies and conditions, as well as people with open wounds should not take Penetrex.


Many joint care products we’ve seen on the market deliver huge marketing claims, but the efficacy of those products is not as good. Unfortunately, Penetrex is one of those products. The proprietary blend and absence of key ingredients in the Joint & Muscle Therapy Cream make it questionable for long-term joint health support.

Similarly, the Joint, Muscle & Nerve Support capsules lack crucial ingredients needed for optimal joint support.

We recommend taking a look at some other joint supplements that provide a more transparent ingredient list and a wider range of essential nutrients.

While Penetrex is a more budget-friendly option, in our years of experience reviewing supplements, we’ve found that the least expensive supplements are usually the least effective.

Considering the value Penetrex provides, we think you’ll get a better bang for your buck with some more expensive supplements that we recommend in our list of best joint supplements.

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