Chondroitin Sulfate and Glucosamine Combination

Chondroitin Sulfate and Glucosamine Combination

Both chondroitin sulfate and glucosamine are very beneficial when it comes to joint health. So, do they provide even higher effects when combined? In this article, we will find the answer to that question. First, let’s talk about some benefits of both of these ingredients.

Glucosamine Sulfate and Chondroitin Comparison

Chondroitin – How Does it Work?

Chondroitin sulfate, a key component of cartilage, acts as a molecular sponge, attracting water and thereby providing cushioning and elasticity to our joints. This nutrient occurs naturally in our body, but you can get it from certain foods as well such as pork skin, chicken feet, and bone broth. By taking it, you can expect some improvement when it comes to pain and inflammation reduction, since this nutrient has anti-inflammatory properties.

Read what the studies say about chondroitin here. We talked about chondroitin earlier in some of our posts which you can read here: Chondroitin Sulfate Mechanism of Action, Is Chondroitin Good For Arthritis?

What About Glucosamine?

Glucosamine can work similarly by helping to reduce pain and inflammation in the long run, however, this nutrient is mainly the precursor to glycosaminoglycans, which are the building blocks of cartilage. Therefore, taking glucosamine can ensure proper cartilage health in the long run.

Can You Take Glucosamine and Chondroitin Together?

Of course you can, just make sure they are in proper doses to avoid any unnecessary side effects, even though they are very rare considering these are completely natural ingredients.

Benefits of Taking Glucosamine and Chondroitin Together

Many studies have shown the efficacy of this duo in promoting joint mobility and comfort. These studies have found that glucosamine and chondroitin taken together can work synergistically to support cartilage integrity, enhance joint function, and alleviate discomfort.

If taken together, they will provide you with much better results when it comes to joint health in the long run than taking a single ingredient. They also both have anti-inflammatory properties, which can help with osteoarthritis and rheumatoid arthritis symptoms as well.

Here is a recent study from the National Library of Medicine which shows us that taking both of these nutrients together resulted in joint function improvement in osteoarthritis patients as well as pain relief.

Glucosamine Sulfate Dosage

There isn’t a precise answer to what the correct dosage of glucosamine is. It all depends on the severity of your joint problems. However, the standard dosage would range from around 1500 to 2000mg each day, and this can be divided into smaller doses.

It’s best to start with smaller doses to see how your body reacts, and then you can gradually increase it. We think 500mg per day with other potent joint nutrients would be a great dosage since it is still effective and safe at the same time. If you are still uncertain, talk to your doctor for more information.

Chondroitin Sulfate Dosage

The standard chondroitin dosage is a bit smaller, at around 750 to 1200mg each day. If you take both glucosamine and chondroitin together, smaller doses would still be quite effective.


Overall, glucosamine and chondroitin taken together are awesome and should help improve your joint health to some degree if taken regularly in the long run. We recommend taking them both through supplements for example, which is the easiest way.

Some premium supplements on the market combine glucosamine, chondroitin, and other joint health nutrients such as turmeric, boswellia, and MSM which all can drastically improve your joint function.

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